The airline has an extensive domestic network, which is complemented by many flights throughout Southeast Asia, and also operates direct flights to Europe and the USA. The Southeast Asia region is usually the cheapest option for departures from Prague, with stable prices around 476 eur to 586 eur throughout the year.
You should buy your tickets through Czech search engines, ideally book 1-2 months in advance for the lowest price. However, there are often limited offers with limited seats even 3 weeks before departure, especially when flying from Prague to SE Asia.